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A clinical odyssey: ulcerative colitis, renal failure, obstructive uropathy, and Streptococcus agalactiae meningoencephalitis

Y. Saipangallu iD, A. Srivastava iD, V. W. Pulikottil iD, R. Vashisht iD, A. Mukherjee iD, M. Bhartiya iD

Sri Lankan Journal of Infectious Diseases 14(2) · 2024

https://doi.org/10.4038/sljid.v14i2.8693

Abstract

Streptococcus agalactiae infections are primarily attributed to pregnancy and neonates. However, adults with underlying immune-compromised states can also be affected. We report a rare instance of GBS meningoencephalitis in a 40-year-old male with chronic kidney disease. The patient presented to us with obstructive uropathy with urinary tract infection. He developed generalised seizures during in-hospital care. Cerebrospinal fluid examination confirmed Streptococcus agalactiae infection. The immunocompromised state of the patient probably contributed to his illness (GBS meningoencephalitis). Early diagnosis by a qualitative multiplexed nucleic acid based in vitro diagnostic test (BioFire ® FilmArray ®) and early treatment helped achieve a successful outcome with no post infection sequelae. This case report demonstrates the importance of early accurate aetiological diagnosis and appropriate treatment to achieve an optimal outcome.

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